Glanzmann Thrombasthenia
Glanzmann thrombasthenia (GT) is a bleeding syndrome characterised by spontaneous mucocutaneous bleeding and an exaggerated response to trauma due to a constitutional thrombocytopenia.
Glanzmann thrombasthenia
a platelet function disorder that is caused by an abnormality in the genes for glycoproteins IIb/IIIa. These genes code for a group of linked proteins normally found on the surface of platelets, the glycoprotein IIb/IIIa receptor (also called the fibrinogen receptor). Because this receptor is absent or is not working properly, platelets do not stick to each other at the site of injury and it is difficult for the normal blood clot to form.
Prevalence
Unknown
Inheritance:
Autosomal recessive
Age of onset:
Infancy, Neonatal
Stay up-to-date with the latest EHC activities and events!